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Altered mTOR Signaling in Senescent Retinal Pigment Epithelium

PURPOSE. Mammalian target of rapamycin (mTOR)-mediated pathways play central roles in regulating aging. The purpose of the present study was to characterize the mTOR cascade in human retinal pigment epithelial (RPE) cells and to investigate its potential roles in controlling RPE senescence. METHODS....

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Hlavní autoři: Chen, Yan, Wang, Jian, Cai, Jiyang, Sternberg, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Association for Research in Vision and Ophthalmology, Inc. 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066610/
https://ncbi.nlm.nih.gov/pubmed/20445122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5280
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