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Altered mTOR Signaling in Senescent Retinal Pigment Epithelium
PURPOSE. Mammalian target of rapamycin (mTOR)-mediated pathways play central roles in regulating aging. The purpose of the present study was to characterize the mTOR cascade in human retinal pigment epithelial (RPE) cells and to investigate its potential roles in controlling RPE senescence. METHODS....
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Association for Research in Vision and Ophthalmology, Inc.
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3066610/ https://ncbi.nlm.nih.gov/pubmed/20445122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5280 |
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