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Altered mTOR Signaling in Senescent Retinal Pigment Epithelium

PURPOSE. Mammalian target of rapamycin (mTOR)-mediated pathways play central roles in regulating aging. The purpose of the present study was to characterize the mTOR cascade in human retinal pigment epithelial (RPE) cells and to investigate its potential roles in controlling RPE senescence. METHODS....

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Detalhes bibliográficos
Main Authors: Chen, Yan, Wang, Jian, Cai, Jiyang, Sternberg, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066610/
https://ncbi.nlm.nih.gov/pubmed/20445122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5280
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