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The mechanistic Target of Rapamycin: The grand conducTOR of metabolism and aging

Since the discovery that rapamycin, a small molecule inhibitor of the protein kinase mTOR (mechanistic Target Of Rapamycin), can extend the lifespan of model organisms including mice, interest in understanding the physiological role and molecular targets of this pathway has surged. While mTOR was al...

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Bibliografski detalji
Izdano u:Cell Metab
Glavni autori: Kennedy, Brian K., Lamming, Dudley W.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910876/
https://ncbi.nlm.nih.gov/pubmed/27304501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.05.009
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