Complement Component C1q Programs a Pro-Efferocytic Phenotype while Limiting TNFα Production in Primary Mouse and Human Macrophages

Deficiency in complement component C1q is associated with an inability to clear apoptotic cells (efferocytosis) and aberrant inflammation in lupus, and identification of the pathways involved in these processes should reveal important regulatory mechanisms in lupus and other autoimmune or inflammato...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hulsebus, Holly J., O’Conner, Sean D., Smith, Emily M., Jie, Chunfa, Bohlson, Suzanne S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908142/
https://ncbi.nlm.nih.gov/pubmed/27379094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00230
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