Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis

Atherosclerosis is the process underlying heart attack and stroke. A characteristic feature of the atherosclerotic plaque is the accumulation of apoptotic cells in the necrotic core. Pro-phagocytic antibody-based therapies are currently being explored to stimulate the phagocytic clearance of apoptot...

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Publicat a:Nat Nanotechnol
Autors principals: Flores, Alyssa M., Hosseini-Nassab, Niloufar, Jarr, Kai-Uwe, Ye, Jianqin, Zhu, Xingjun, Wirka, Robert, Koh, Ai Leen, Tsantilas, Pavlos, Wang, Ying, Nanda, Vivek, Kojima, Yoko, Zeng, Yitian, Lotfi, Mozhgan, Sinclair, Robert, Weissman, Irving L., Ingelsson, Erik, Smith, Bryan Ronain, Leeper, Nicholas J.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254969/
https://ncbi.nlm.nih.gov/pubmed/31988506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41565-019-0619-3
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