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Complement component C1q regulates macrophage expression of Mer tyrosine kinase to promote clearance of apoptotic cells

Failure to efficiently clear apoptotic cells is linked to defects in development and the onset of autoimmunity. Complement component C1q is required for efficient engulfment of apoptotic cells in mice and humans, however, the molecular mechanisms leading to C1q-dependent engulfment are not fully und...

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Main Authors: Galvan, Manuel D., Foreman, Deborah B., Zeng, Erliang, Tan, John C., Bohlson, Suzanne S.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324645/
https://ncbi.nlm.nih.gov/pubmed/22422887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102920
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