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Complement Component C1q Programs a Pro-Efferocytic Phenotype while Limiting TNFα Production in Primary Mouse and Human Macrophages

Deficiency in complement component C1q is associated with an inability to clear apoptotic cells (efferocytosis) and aberrant inflammation in lupus, and identification of the pathways involved in these processes should reveal important regulatory mechanisms in lupus and other autoimmune or inflammato...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Immunol
Egile Nagusiak: Hulsebus, Holly J., O’Conner, Sean D., Smith, Emily M., Jie, Chunfa, Bohlson, Suzanne S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908142/
https://ncbi.nlm.nih.gov/pubmed/27379094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00230
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