Efferocytic Defects in Early Atherosclerosis Are Driven by GATA2 Overexpression in Macrophages

The loss of efferocytosis—the phagocytic clearance of apoptotic cells—is an initiating event in atherosclerotic plaque formation. While the loss of macrophage efferocytosis is a prerequisite for advanced plaque formation, the transcriptional and cellular events in the pre-lesion site that drive thes...

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Опубликовано в: :Front Immunol
Главные авторы: Yin, Charles, Vrieze, Angela M., Rosoga, Mara, Akingbasote, James, Pawlak, Emily N., Jacob, Rajesh Abraham, Hu, Jonathan, Sharma, Neha, Dikeakos, Jimmy D., Barra, Lillian, Nagpal, A. Dave, Heit, Bryan
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644460/
https://ncbi.nlm.nih.gov/pubmed/33193444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.594136
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