Efferocytic Defects in Early Atherosclerosis Are Driven by GATA2 Overexpression in Macrophages

The loss of efferocytosis—the phagocytic clearance of apoptotic cells—is an initiating event in atherosclerotic plaque formation. While the loss of macrophage efferocytosis is a prerequisite for advanced plaque formation, the transcriptional and cellular events in the pre-lesion site that drive thes...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Yin, Charles, Vrieze, Angela M., Rosoga, Mara, Akingbasote, James, Pawlak, Emily N., Jacob, Rajesh Abraham, Hu, Jonathan, Sharma, Neha, Dikeakos, Jimmy D., Barra, Lillian, Nagpal, A. Dave, Heit, Bryan
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644460/
https://ncbi.nlm.nih.gov/pubmed/33193444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.594136
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