Efferocytic Defects in Early Atherosclerosis Are Driven by GATA2 Overexpression in Macrophages

The loss of efferocytosis—the phagocytic clearance of apoptotic cells—is an initiating event in atherosclerotic plaque formation. While the loss of macrophage efferocytosis is a prerequisite for advanced plaque formation, the transcriptional and cellular events in the pre-lesion site that drive thes...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Yin, Charles, Vrieze, Angela M., Rosoga, Mara, Akingbasote, James, Pawlak, Emily N., Jacob, Rajesh Abraham, Hu, Jonathan, Sharma, Neha, Dikeakos, Jimmy D., Barra, Lillian, Nagpal, A. Dave, Heit, Bryan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644460/
https://ncbi.nlm.nih.gov/pubmed/33193444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.594136
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