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Rotavirus NSP1 Associates with Components of the Cullin RING Ligase Family of E3 Ubiquitin Ligases

The rotavirus nonstructural protein NSP1 acts as an antagonist of the host antiviral response by inducing degradation of key proteins required to activate interferon (IFN) production. Protein degradation induced by NSP1 is dependent on the proteasome, and the presence of a RING domain near the N ter...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Lutz, Lindy M., Pace, Chandler R., Arnold, Michelle M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907217/
https://ncbi.nlm.nih.gov/pubmed/27099313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00704-16
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