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Rotavirus NSP1 Associates with Components of the Cullin RING Ligase Family of E3 Ubiquitin Ligases

The rotavirus nonstructural protein NSP1 acts as an antagonist of the host antiviral response by inducing degradation of key proteins required to activate interferon (IFN) production. Protein degradation induced by NSP1 is dependent on the proteasome, and the presence of a RING domain near the N ter...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Lutz, Lindy M., Pace, Chandler R., Arnold, Michelle M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907217/
https://ncbi.nlm.nih.gov/pubmed/27099313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00704-16
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