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Rotavirus NSP1 Associates with Components of the Cullin RING Ligase Family of E3 Ubiquitin Ligases

The rotavirus nonstructural protein NSP1 acts as an antagonist of the host antiviral response by inducing degradation of key proteins required to activate interferon (IFN) production. Protein degradation induced by NSP1 is dependent on the proteasome, and the presence of a RING domain near the N ter...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Lutz, Lindy M., Pace, Chandler R., Arnold, Michelle M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907217/
https://ncbi.nlm.nih.gov/pubmed/27099313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00704-16
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