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The endoplasmic reticulum may be an Achilles' heel of cancer cells that have undergone an epithelial-to-mesenchymal transition

In a recent report published in Cancer Discovery we identified a novel vulnerability of cancer cells that have undergone an epithelial–mesenchymal transition (EMT) and established that the PERK branch of the unfolded protein response is constitutively activated upon EMT. In this commentary, we summa...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Oncol
Prif Awduron: Feng, Yu-xiong, Sokol, Ethan S, Gupta, Piyush B
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905182/
https://ncbi.nlm.nih.gov/pubmed/27308337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.961822
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