Alveolar Epithelial Cells Undergo Epithelial-to-Mesenchymal Transition in Response to Endoplasmic Reticulum Stress

Expression of mutant surfactant protein C (SFTPC) results in endoplasmic reticulum (ER) stress in type II alveolar epithelial cells (AECs). AECs have been implicated as a source of lung fibroblasts via epithelial-to-mesenchymal transition (EMT); therefore, we investigated whether ER stress contribut...

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Autors principals: Tanjore, Harikrishna, Cheng, Dong-Sheng, Degryse, Amber L., Zoz, Donald F., Abdolrasulnia, Rasul, Lawson, William E., Blackwell, Timothy S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162456/
https://ncbi.nlm.nih.gov/pubmed/21757695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.181164
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