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The endoplasmic reticulum may be an Achilles' heel of cancer cells that have undergone an epithelial-to-mesenchymal transition

In a recent report published in Cancer Discovery we identified a novel vulnerability of cancer cells that have undergone an epithelial–mesenchymal transition (EMT) and established that the PERK branch of the unfolded protein response is constitutively activated upon EMT. In this commentary, we summa...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cell Oncol
Päätekijät: Feng, Yu-xiong, Sokol, Ethan S, Gupta, Piyush B
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905182/
https://ncbi.nlm.nih.gov/pubmed/27308337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.961822
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