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The endoplasmic reticulum may be an Achilles' heel of cancer cells that have undergone an epithelial-to-mesenchymal transition

In a recent report published in Cancer Discovery we identified a novel vulnerability of cancer cells that have undergone an epithelial–mesenchymal transition (EMT) and established that the PERK branch of the unfolded protein response is constitutively activated upon EMT. In this commentary, we summa...

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Foilsithe in:Mol Cell Oncol
Main Authors: Feng, Yu-xiong, Sokol, Ethan S, Gupta, Piyush B
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905182/
https://ncbi.nlm.nih.gov/pubmed/27308337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.961822
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