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Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells
BACKGROUND: Pancreatic β cell dysfunction and death are central in the pathogenesis of most if not all forms of diabetes. Understanding the molecular mechanisms underlying β cell failure is important to develop β cell protective approaches. SCOPE OF REVIEW: Here we review the role of endoplasmic ret...
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| Udgivet i: | Mol Metab |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5605732/ https://ncbi.nlm.nih.gov/pubmed/28951826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.06.001 |
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