Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells

BACKGROUND: Pancreatic β cell dysfunction and death are central in the pathogenesis of most if not all forms of diabetes. Understanding the molecular mechanisms underlying β cell failure is important to develop β cell protective approaches. SCOPE OF REVIEW: Here we review the role of endoplasmic ret...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Metab
Autores principales: Cnop, Miriam, Toivonen, Sanna, Igoillo-Esteve, Mariana, Salpea, Paraskevi
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605732/
https://ncbi.nlm.nih.gov/pubmed/28951826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.06.001
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares