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AMBRA1-induced mitophagy: A new mechanism to cope with cancer?
Dysfunctions in mitophagy, the process by which mitochondria are eliminated, are associated with cancer. We found that the proautophagic protein AMBRA1 (activating molecule in beclin 1 regulated autophagy) binds the autophagosome adapter LC3, and that this interaction is crucial for mitochondrial cl...
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| Published in: | Mol Cell Oncol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4904902/ https://ncbi.nlm.nih.gov/pubmed/27308437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.975647 |
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