AMBRA1-Mediated Mitophagy Counteracts Oxidative Stress and Apoptosis Induced by Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells

Therapeutic strategies are needed to protect dopaminergic neurons in Parkinson’s disease (PD) patients. Oxidative stress caused by dopamine may play an important role in PD pathogenesis. Selective autophagy of mitochondria (mitophagy), mainly regulated by PINK1 and PARKIN, plays an important role in...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Anthea Di Rita, Pasquale D’Acunzo, Luca Simula, Silvia Campello, Flavie Strappazzon, Francesco Cecconi
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018-04-01
Serija:Frontiers in Cellular Neuroscience
Teme:
cell death
oxidative stress
in vitro models
Parkinson’s disease
mitophagy
Online pristup:http://journal.frontiersin.org/article/10.3389/fncel.2018.00092/full
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items