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AMBRA1-induced mitophagy: A new mechanism to cope with cancer?
Dysfunctions in mitophagy, the process by which mitochondria are eliminated, are associated with cancer. We found that the proautophagic protein AMBRA1 (activating molecule in beclin 1 regulated autophagy) binds the autophagosome adapter LC3, and that this interaction is crucial for mitochondrial cl...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4904902/ https://ncbi.nlm.nih.gov/pubmed/27308437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.975647 |
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