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AMBRA1-induced mitophagy: A new mechanism to cope with cancer?

Dysfunctions in mitophagy, the process by which mitochondria are eliminated, are associated with cancer. We found that the proautophagic protein AMBRA1 (activating molecule in beclin 1 regulated autophagy) binds the autophagosome adapter LC3, and that this interaction is crucial for mitochondrial cl...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Oncol
Asıl Yazarlar: Strappazzon, Flavie, Cecconi, Francesco
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904902/
https://ncbi.nlm.nih.gov/pubmed/27308437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.975647
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