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A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: application to acetaminophen
Obesity and nonalcoholic fatty liver disease (NAFLD) can increase susceptibility to hepatotoxicity induced by some xenobiotics including drugs, but the involved mechanisms are poorly understood. For acetaminophen (APAP), a role of hepatic cytochrome P450 2E1 (CYP2E1) is suspected since the activity...
Zapisane w:
| Wydane w: | Toxicol Appl Pharmacol |
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| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4904302/ https://ncbi.nlm.nih.gov/pubmed/26739624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.12.020 |
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