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Mechanistic Biomarkers in Acetaminophen-induced Hepatotoxicity and Acute Liver Failure: From Preclinical Models to Patients
INTRODUCTION: Drug hepatotoxicity is a major clinical issue. Acetaminophen (APAP) overdose is especially common. Serum biomarkers used to follow patient progress reflect either liver injury or function, but focus on biomarkers that can provide insight into the basic mechanisms of hepatotoxicity is i...
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| Veröffentlicht in: | Expert Opin Drug Metab Toxicol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4414250/ https://ncbi.nlm.nih.gov/pubmed/24836926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2014.920823 |
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