Acetaminophen-induced Liver Injury: from Animal Models to Humans

Drug-induced liver injury is an important clinical problem and a challenge for drug development. Whereas progress in understanding rare and unpredictable (idiosyncratic) drug hepatotoxicity is severely hampered by the lack of relevant animal models, enormous insight has been gained in the area of pr...

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Bibliographic Details
Published in:J Clin Transl Hepatol
Main Authors: Jaeschke, Hartmut, Xie, Yuchao, McGill, Mitchell R.
Format: Artigo
Language:Inglês
Published: XIA & HE Publishing Ltd 2014
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521247/
https://ncbi.nlm.nih.gov/pubmed/26355817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14218/JCTH.2014.00014
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