Protein methionine oxidation augments reperfusion injury in acute ischemic stroke

Reperfusion injury can exacerbate tissue damage in ischemic stroke, but little is known about the mechanisms linking ROS to stroke severity. Here, we tested the hypothesis that protein methionine oxidation potentiates NF-κB activation and contributes to cerebral ischemia/reperfusion injury. We found...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Gu, Sean X., Blokhin, Ilya O., Wilson, Katina M., Dhanesha, Nirav, Doddapattar, Prakash, Grumbach, Isabella M., Chauhan, Anil K., Lentz, Steven R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902298/
https://ncbi.nlm.nih.gov/pubmed/27294204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86460
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