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Sequence Context Influences the Structure and Aggregation Behavior of a PolyQ Tract
Expansions of polyglutamine (polyQ) tracts in nine different proteins cause a family of neurodegenerative disorders called polyQ diseases. Because polyQ tracts are potential therapeutic targets for these pathologies there is great interest in characterizing the conformations that they adopt and in u...
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| 出版年: | Biophys J |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4900447/ https://ncbi.nlm.nih.gov/pubmed/27276254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.022 |
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