Sequence Context Influences the Structure and Aggregation Behavior of a PolyQ Tract

Expansions of polyglutamine (polyQ) tracts in nine different proteins cause a family of neurodegenerative disorders called polyQ diseases. Because polyQ tracts are potential therapeutic targets for these pathologies there is great interest in characterizing the conformations that they adopt and in u...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Eftekharzadeh, Bahareh, Piai, Alessandro, Chiesa, Giulio, Mungianu, Daniele, García, Jesús, Pierattelli, Roberta, Felli, Isabella C., Salvatella, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900447/
https://ncbi.nlm.nih.gov/pubmed/27276254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.022
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados