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Ataxin-1 Fusion Partners Alter PolyQ Lethality and Aggregation

Intranuclear inclusion bodies (IBs) are the histopathologic markers of multiple protein folding diseases. IB formation has been extensively studied using fluorescent fusion products of pathogenic polyglutamine (polyQ) expressing proteins. These studies have been informative in determining the cellul...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rich, Tina, Varadaraj, Archana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995763/
https://ncbi.nlm.nih.gov/pubmed/17925862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001014
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