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PolyQ-expanded ataxin-3 interacts with full-length ataxin-3 in a polyQ length-dependent manner
OBJECTIVE: Machado-Joseph disease (MJD), also known as spinocerebellar ataxia type 3 (SCA3), is a dominant neurodegenerative disorder caused by an expansion of the polyglutamine (polyQ) tract in MJD-1 gene product, ataxin-3 (AT3). This disease is characterized by the formation of intraneuronal inclu...
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| Publicado no: | Neurosci Bull |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5552588/ https://ncbi.nlm.nih.gov/pubmed/18668148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-008-0326-9 |
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