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PolyQ-expanded ataxin-3 interacts with full-length ataxin-3 in a polyQ length-dependent manner

OBJECTIVE: Machado-Joseph disease (MJD), also known as spinocerebellar ataxia type 3 (SCA3), is a dominant neurodegenerative disorder caused by an expansion of the polyglutamine (polyQ) tract in MJD-1 gene product, ataxin-3 (AT3). This disease is characterized by the formation of intraneuronal inclu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurosci Bull
Prif Awduron: Jia, Na-Li, Fei, Er-Kang, Ying, Zheng, Wang, Hong-Feng, Wang, Guang-Hui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552588/
https://ncbi.nlm.nih.gov/pubmed/18668148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-008-0326-9
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