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Distinct TDP-43 pathology in ALS patients with ataxin 2 intermediate-length polyQ expansions
Amyotrophic lateral sclerosis (ALS) is a progressive, adult-onset neurodegenerative disease characterized by degeneration of motor neurons, resulting in paralysis and death. A pathological hallmark of the degenerating motor neurons in most ALS patients is the presence of cytoplasmic inclusions conta...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3543833/ https://ncbi.nlm.nih.gov/pubmed/22526021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-0985-5 |
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