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Cryo-EM reveals the steric zipper structure of a light chain-derived amyloid fibril
Amyloid fibrils are proteinaceous aggregates associated with diseases in humans and animals. The fibrils are defined by intermolecular interactions between the fibril-forming polypeptide chains, but it has so far remained difficult to reveal the assembly of the peptide subunits in a full-scale fibri...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4896715/ https://ncbi.nlm.nih.gov/pubmed/27185936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522282113 |
| Oznake: |
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