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Paired β-sheet structure of an Aβ(1-40) amyloid fibril revealed by electron microscopy
Alzheimer's disease is a neurodegenerative disorder that is characterized by the cerebral deposition of amyloid fibrils formed by Aβ peptide. Despite their prevalence in Alzheimer's and other neurodegenerative diseases, important details of the structure of amyloid fibrils remain unknown....
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396686/ https://ncbi.nlm.nih.gov/pubmed/18483195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712290105 |
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