Llwytho...

Cryo-EM reveals the steric zipper structure of a light chain-derived amyloid fibril

Amyloid fibrils are proteinaceous aggregates associated with diseases in humans and animals. The fibrils are defined by intermolecular interactions between the fibril-forming polypeptide chains, but it has so far remained difficult to reveal the assembly of the peptide subunits in a full-scale fibri...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Schmidt, Andreas, Annamalai, Karthikeyan, Schmidt, Matthias, Grigorieff, Nikolaus, Fändrich, Marcus
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896715/
https://ncbi.nlm.nih.gov/pubmed/27185936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522282113
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!