Physical basis of amyloid fibril polymorphism

Polymorphism is a key feature of amyloid fibril structures but it remains challenging to explain these variations for a particular sample. Here, we report electron cryomicroscopy-based reconstructions from different fibril morphologies formed by a peptide fragment from an amyloidogenic immunoglobuli...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Close, William, Neumann, Matthias, Schmidt, Andreas, Hora, Manuel, Annamalai, Karthikeyan, Schmidt, Matthias, Reif, Bernd, Schmidt, Volker, Grigorieff, Nikolaus, Fändrich, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816019/
https://ncbi.nlm.nih.gov/pubmed/29453354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03164-5
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