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Recent progress in understanding Alzheimer’s β-amyloid structures

The formation of amyloid fibrils, protofibrils and oligomers from the β-amyloid (Aβ) peptide represents a hallmark of Alzheimer’s disease. Aβ peptide-derived assemblies might be crucial for disease onset, but determining their atomic structures has proven to be a major challenge. Progress over the l...

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Bibliografiske detaljer
Main Authors: Fändrich, Marcus, Schmidt, Matthias, Grigorieff, Nikolaus
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144754/
https://ncbi.nlm.nih.gov/pubmed/21411326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2011.02.002
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