Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids

Systemic AA amyloidosis is a worldwide occurring protein misfolding disease of humans and animals. It arises from the formation of amyloid fibrils from the acute phase protein serum amyloid A. Here, we report the purification and electron cryo-microscopy analysis of amyloid fibrils from a mouse and...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Liberta, Falk, Loerch, Sarah, Rennegarbe, Matthies, Schierhorn, Angelika, Westermark, Per, Westermark, Gunilla T., Hazenberg, Bouke P. C., Grigorieff, Nikolaus, Fändrich, Marcus, Schmidt, Matthias
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405766/
https://ncbi.nlm.nih.gov/pubmed/30846696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09033-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items