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Paired β-sheet structure of an Aβ(1-40) amyloid fibril revealed by electron microscopy

Alzheimer's disease is a neurodegenerative disorder that is characterized by the cerebral deposition of amyloid fibrils formed by Aβ peptide. Despite their prevalence in Alzheimer's and other neurodegenerative diseases, important details of the structure of amyloid fibrils remain unknown....

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Detalles Bibliográficos
Main Authors: Sachse, Carsten, Fändrich, Marcus, Grigorieff, Nikolaus
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396686/
https://ncbi.nlm.nih.gov/pubmed/18483195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712290105
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