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Paired β-sheet structure of an Aβ(1-40) amyloid fibril revealed by electron microscopy

Alzheimer's disease is a neurodegenerative disorder that is characterized by the cerebral deposition of amyloid fibrils formed by Aβ peptide. Despite their prevalence in Alzheimer's and other neurodegenerative diseases, important details of the structure of amyloid fibrils remain unknown....

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Bibliografski detalji
Glavni autori: Sachse, Carsten, Fändrich, Marcus, Grigorieff, Nikolaus
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396686/
https://ncbi.nlm.nih.gov/pubmed/18483195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712290105
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