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α-Mangostin Inhibits α-Synuclein-Induced Microglial Neuroinflammation and Neurotoxicity
Microglia-mediated neuroinflammation induced by α-synuclein in the substantianigra likely either initiates or aggravates nigral neuro degeneration in Parkinson’s disease (PD). We aimed to explore the effects of α-mangostin (α-M), a polyphenolicxanthone derivative from mangosteen on α-synuclein-stimu...
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| Udgivet i: | Cell Mol Neurobiol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer US
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4894924/ https://ncbi.nlm.nih.gov/pubmed/27002719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-015-0264-9 |
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