Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration

Parkinson's Disease (PD) is an age-related, chronic neurodegenerative disorder. At present, there are no disease-modifying therapies to prevent PD progression. Activated microglia and neuroinflammation are associated with the pathogenesis and progression of PD. Accumulation of α-synuclein (α-SY...

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Publicado en:J Neurosci
Autores principales: Qin, Hongwei, Buckley, Jessica A., Li, Xinru, Liu, Yudong, Fox, Thomas H., Meares, Gordon P., Yu, Hao, Yan, Zhaoqi, Harms, Ashley S., Li, Yufeng, Standaert, David G., Benveniste, Etty N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2016
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123006/
https://ncbi.nlm.nih.gov/pubmed/27147665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4658-15.2016
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