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Treatment with Histone Deacetylase Inhibitor Attenuates MAP Kinase Mediated Liver Injury in a Lethal Model of Septic Shock()

BACKGROUND: Despite global efforts to improve the treatment of sepsis, it remains a leading cause of morbidity and mortality in intensive care units. We have previously shown that suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor, markedly improves survival in a murine model of...

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Bibliografiset tiedot
Julkaisussa:J Surg Res
Päätekijät: Finkelstein, Robert A., Li, Yongqing, Liu, Baoling, Shuja, Fahad, Fukudome, Eugene, Velmahos, George C., deMoya, Marc, Alam, Hasan B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894321/
https://ncbi.nlm.nih.gov/pubmed/20599223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2010.04.024
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