Surviving lethal septic shock without fluid resuscitation in a rodent model

BACKGROUND: We have recently demonstrated that treatment with suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor, before a lethal dose of lipopolysaccharide (LPS) improves survival in mice. The purpose of the present study was to determine whether SAHA treatment would attenuate...

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Bibliographic Details
Published in:Surgery
Main Authors: Li, Yongqing, Liu, Baoling, Fukudome, Eugene Y., Kochanek, Ashley R., Finkelstein, Robert A., Chong, Wei, Jin, Guang, Lu, Jennifer, deMoya, Marc A., Velmahos, George C., Alam, Hasan B.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894305/
https://ncbi.nlm.nih.gov/pubmed/20561658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2010.05.003
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