Histone Deacetylase Inhibitors Prevent Apoptosis following Lethal Hemorrhagic Shock in Rodent Kidney Cells

BACKGROUND: We have previously demonstrated that treatment with histone deacetylase inhibitors (HDACI), such as valproic acid (VPA) and suberoylanilide hydroxamic acid (SAHA), can improve survival after hemorrhagic shock in animal models. Hemorrhage results in hypoacetylation of proteins which is re...

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Detaylı Bibliyografya
Yayımlandı:Resuscitation
Asıl Yazarlar: Zacharias, Nikolaos, Sailhamer, Elizabeth A., Li, Yongqing, Liu, Baoling, Butt, Muhammad U., Shuja, Fahad, Velmahos, George C., de Moya, Marc, Alam, Hasan B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361066/
https://ncbi.nlm.nih.gov/pubmed/21036453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resuscitation.2010.09.469
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