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Histone Deacetylase Inhibitor Treatment Attenuates Coagulation Imbalance in a Lethal Sepsis Model

BACKGROUND: Sepsis has a profound impact on the inflammatory and hemostatic systems. In addition to systemic inflammation, it can produce disseminated intravascular coagulation, microvascular thrombosis, consumptive coagulopathy, and multiple organ failure. We have shown that treatment with suberoyl...

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Detalhes bibliográficos
Publicado no:Surgery
Main Authors: Zhao, Ting, Li, Yongqing, Liu, Baoling, Wu, Erxi, Sillesen, Martin, Velmahos, George C., Halaweish, Ihab, Alam, Hasan B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267526/
https://ncbi.nlm.nih.gov/pubmed/24957668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2014.04.022
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