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Histone Deacetylase III as a Potential Therapeutic Target for the Treatment of Lethal Sepsis
BACKGROUND: We have recently demonstrated that inhibition of histone deacetylase (HDAC) class I, II and IV with non-specific HDAC inhibitors improves survival in a mouse model of lethal cecal ligation and puncture (CLP). However, the consequence of HDAC class III inhibition is unknown in this model....
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| Published in: | J Trauma Acute Care Surg |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824316/ https://ncbi.nlm.nih.gov/pubmed/25051385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000000347 |
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