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Selective Histone Deacetylase-6 Inhibition Attenuates Stress Responses and Prevents Immune Organ Atrophy in a Lethal Septic Model
BACKGROUND: An overproduction of corticosterone during severe sepsis results in increased apoptosis of immune cells, which may result in relative immunosuppression and an impaired ability to fight infections. We have previously demonstrated that administration of Tubastatin A, a selective inhibitor...
Gorde:
| Argitaratua izan da: | Surgery |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267495/ https://ncbi.nlm.nih.gov/pubmed/24947640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2014.03.033 |
| Etiketak: |
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