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Histone Deacetylase Inhibitors: Isoform Selectivity Improves Survival in a Hemorrhagic Shock Model
BACKGROUND: Hemorrhage is a leading preventable cause of death. Non-selective histone deacetylase inhibitors (HDACIs), such as valproic acid (VPA), have been shown to improve outcomes in hemorrhagic shock (HS). HDACs can be divided into 4 functional classes (I, IIa/IIb, III & IV). Classes I, IIa...
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| 出版年: | J Trauma Acute Care Surg |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6318805/ https://ncbi.nlm.nih.gov/pubmed/29401190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000001824 |
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