Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins

The evolutionary origins of the gene network underlying cellular pluripotency, a central theme in developmental biology, have yet to be elucidated. In mammals, Oct4 is a factor crucial in the reprogramming of differentiated cells into induced pluripotent stem cells. The Oct4 and Pou2 genes evolved f...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Tapia, Natalia, Reinhardt, Peter, Duemmler, Annett, Wu, Guangming, Araúzo-Bravo, Marcos J., Esch, Daniel, Greber, Boris, Cojocaru, Vlad, Rascon, Cynthia Alexander, Tazaki, Akira, Kump, Kevin, Voss, Randal, Tanaka, Elly M., Schöler, Hans R.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892893/
https://ncbi.nlm.nih.gov/pubmed/23232409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2229
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares