Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins

The evolutionary origins of the gene network underlying cellular pluripotency, a central theme in developmental biology, have yet to be elucidated. In mammals, Oct4 is a factor crucial in the reprogramming of differentiated cells into induced pluripotent stem cells. The Oct4 and Pou2 genes evolved f...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Tapia, Natalia, Reinhardt, Peter, Duemmler, Annett, Wu, Guangming, Araúzo-Bravo, Marcos J., Esch, Daniel, Greber, Boris, Cojocaru, Vlad, Rascon, Cynthia Alexander, Tazaki, Akira, Kump, Kevin, Voss, Randal, Tanaka, Elly M., Schöler, Hans R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892893/
https://ncbi.nlm.nih.gov/pubmed/23232409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2229
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